News Release




June 14, 2007

State Board of Education Awards Boise State
$1 Million to Establish Center for Musculoskeletal Research

New center will focus on causes and treatments for osteoarthritis

The State Board of Education today unanimously approved a $1 million grant to Boise State University to establish a major biomedical research center to coordinate studies on osteoarthritis, a disease that affects over 30 percent of the U.S. population and costs $124 billion each year to diagnose and treat.

The new Center for Musculoskeletal Research was selected for funding as part of a competitive statewide process that also included proposals from the University of Idaho and Idaho State University. A seven-member team of administrators and scientists from outside Idaho reviewed the proposals from Boise State and other universities and conducted on-site evaluations at each campus earlier this year. Following the visits, the team recommended to the State Board’s Higher Education Research Council that the Boise State proposal be funded.

“The Center for Musculoskeletal Research will provide support, momentum and visibility for Boise State’s growing biomolecular research programs, and it will also serve as a catalyst for new research collaborations,” said Vice President for Research Mark Rudin. “Our undergraduate and graduate students will benefit by working alongside faculty on new research projects. This is another step forward for Boise State as a metropolitan research university of distinction.”

The center brings together Boise State faculty in biology, engineering, kinesiology, computer science, chemistry and other fields for interdisciplinary research projects that range from molecular interactions to whole-body motions. In addition, the center will collaborate with the Boise medical community and other research institutions in Idaho and the nation on studies that could lead to new treatments for the devastating disease.

Strong support from Boise’s medical community, along with outstanding faculty that are already engaged in interdisciplinary research, contributed to the success of Boise State’s proposal, said Lee Weber, a University of Nevada-Reno professor and director of that state’s biomedical research network who was a member of the evaluation team.

“Because Idaho doesn’t have a medical school, having strong support from local doctors is crucial if you’re going to be able to conduct biomedical research,” said Weber. “We were very impressed with the level of interest among doctors with whom we met.”

Dr. Michael Coughlin, a Boise orthopedic surgeon and nationally recognized researcher on the foot and ankle, was among physicians who supported the new center. “Focusing research here in Boise and at Boise State makes good sense because we have the scientific researchers, the labs and equipment, and the know-how to get it done,” Coughlin said. “You couple Boise State with the interest and involvement of the local medical community — this gives us a vibrant research platform.”

Kinesiology professor Ron Pfeiffer will be director of the new center. Biology professor Julie Oxford, the principal investigator on the grant, will be the associate director for molecular and cellular processes, and mechanical and biomedical engineering professor Michelle Sabick will be the associate director for biomechanics. Eleven other Boise State faculty from a variety of disciplines are also affiliated with the center.

The Center for Musculoskeletal Research will initially undertake two projects. The first will be a study to identify the molecular signal that triggers the onset of arthritis in a group of patients who have suffered knee injuries involving the anterior cruciate ligament. A second project will develop a computer model that identifies molecular markers for arthritis in genetically modified mice that are predisposed to develop the disease.

Both projects involve an interdisciplinary team of researchers, and, in the case of the ACL study, will also involve Boise area physicians who will extract synovial fluid from the knees of participants for genetic analysis as part of the project.

The center will also support ongoing Boise State research involving genetic susceptibility for arthritis. These studies include research on the structure and function of cartilage, gender-related differences in ACL injuries to the knee, bone metastasis in breast cancer, assessing the effectiveness of diagnostic tests for certain types of shoulder injuries, computer modeling of molecular studies, and other projects.

Scientific instrumentation acquired in recent years as part of research grants from the National Science Foundation and other funding sources will be an integral part of the new center and its research mission. Located in laboratories across campus, the instrumentation includes microscopy systems that allow material to be studied on a near-atomic level, a cluster of linked computers that function as a super-computing system, state-of-the-art computer animation technology and other equipment.

“As Boise State continues to expand its research programs in biomolecular sciences, this new center will help lead the way,” Rudin said. “The positive impact will be felt across campus in our classrooms and our research laboratories, and it will help strengthen the culture of excellence that is part of Boise State.”

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Contact: Mark Rudin, Vice President for Research, (208) 426-5732, markrudin@boisestate.edu
Ron Pfeiffer, Department of Kinesiology, (208) 426-3709, Pfeiffer@boistate.edu
Julie Oxford, Department of Biology, (208) 426-2395, joxford@boisestate.edu
Media contact: Janelle Brown, University Communications, (208) 426-1790, jbrown2@boisestate.edu

Boise State University is the largest institution of higher education in Idaho, offering more than 190 fields of interest in eight colleges. The deadline for degree-seeking students to apply for fall admission is July 18. Discover the New U Beyond the Blue.
 



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Last reviewed on Thursday, June 14, 2007